PhD Student

Email: weh26@cam.ac.uk

Research interests

During my undergraduate degree in Biomedicine at the University of Newcastle, I first came in contact with the fascinating topic of regenerative medicine. In order to pursue this scientific interest I continued with my research with a Masters by research in stem cells and regenerative medicine at Newcastle. During that time I fist encountered Mesenchymal Stem Cell derived Extracellular Vesicles with Dr Xiao Nong Wang.

In October 2018 I joined the Division of Trauma and Orthopaedic Surgery as a PhD student working on bone marrow derived Mesenchymal Stem Cells and their extracellular vesicles.

Key publications

Hotham WE. A Sprinkling of Gold Dust: Fairytale or Modern Science. Blue Sci 2021 Issue 50

Hotham WE, Henson FMD. The use of large animals to facilitate the process of MSC going from laboratory to patient-‘bench to bedside’. Cell Biology and Toxicology. 2020 Mar 23 [Epub]

Hotham WE, Malviya A. A systematic review of surgical methods to restore articular cartilage in the hip. Bone Joint Res. 2018 May; 7(5): 336–342.

Leitch AC, Lakey AF, W.E.Hotham, Agius L, Kass GEN, Blain PG, Wright MC. The ionic liquid 1-octyl-3-methylimidazolium (M8OI) is an activator of the human estrogen receptor alpha. Biochem Biophys Res Commun. 2018 Sep 10;503(3):2167-2172.