Research Fellow, Division of Trauma and Orthopaedic Surgery
Senior Lecturer in Equine Surgery
Email: fmdh1@cam.ac.uk
Research Interests
Dr Henson is a University Senior Lecturer in the Department of Veterinary Medicine and a Research Fellow in the Department of Surgery. Her research interests are in the pathophysiology of joint disease and repair.
Her particular areas of active research interest include the use of autologous cells, biological factors and biosynthetic scaffolds to repair musculoskeletal damage, the response of cartilage to load (with particular emphasis on the response of the serine protease HtrA1) and the role of the wnt signalling pathway inhibitor, sclerostin, in joint damage and repair. She is also interested in stem cell tracking and in developing novel methods for detecting tracked cells through advanced imaging and is the UK Lead on the EU funded STARSTEM project and is a member of the Tissue Engineering Centre funded by ARUK.
Recent publications.
Hotham WE, Henson FMD. The use of large animals to facilitate the process of MSC going from laboratory to patient-‘bench to bedside’. Cell Biology and Toxicology. 2020 Mar 23 [Epub]
Whitty, C., Wardale, R.J. and Henson F.M.D. (2018) The regulation of sclerostin by cathepsin K in periodontal ligament cells. Biochemical Biophyical Research Communications 503 550-555.
Baird, A., Lindsay, T., Everett, A., Paterson, Y.Z., McClellan, A., Henson F.M.D. and Guest D. (2018) Osteoblast differentiation of equine induced pluripotent stem cells. Biology Open
Lydon, H., Brooks, R., McCaskie, A.W. and Henson F.M.D. (2018) Peripheral mononuclear blood cell apheresis in a preclinical ovine model. BMC Veterinary Research 14 47.
Hopper N., Singer, E. and Henson F.M.D. (2018) Increased sclerostin associated with stress fracture of the third metacarpal bone in the TB racehorse. Bone and Joint Research7 94-102
Newell, K., Chitty, J. and Henson F.M.D. (2018) “Patient reported outcomes” following experimental surgery – using telemetry to assess movement in experimental ovine models. Journal of Orthopaedic Research 36 1498-1507
Lydon, H., Getgood, A. and Henson F.M.D. (2017) Healing of Osteochondral defects via endochondral ossification in an ovine model. Cartilage
A full list of publications can be found at Google scholar
Areas of expertise
cartilage osteochondral defects, joint surface repair, stem cells, animal models