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Orthopaedic Research Unit

 

School of Clinical Medicine > Orthopaedic Research Unit

 

 

Current Research

 

Combining Cell Lineages for Enhanced Joint Tissue Regeneration
JA Wardale and N Rushton

Support: Stryker

Stem cells for cartilage repair and regeneration

N Hooper, JA Wardale, N Rushton

 

Support: John Insall Foundation

 

Collagen scaffolds with aligned porosity

K Pawelec, JA Wardale, RE Cameron

 

Support: Gates Foundation

 

Development of a smart implant for meniscus repair using PRP-mediated biological repair

D Howard, N Rushton

 

Support: NIHR i4i

 

Modulating the response of impaction loading to articular cartilage

P Hernandez-Valdez, FMD Henson, N Rushton

 

Support: Merck KGaA

 

The augmentation of microfracture with rhFGF18

FMD Henson, J Power, AM Getgood, N Rushton

 

Support: Merck KGaA

 

Artificial ligament with bioactive nanostructure

Z Ahmad, RA Brooks, JA Wardale, N Rushton

 

Support: EPSRC

 

Skeletal site variation in bone cell behaviour

RA Brooks, N Loveridge, N Rushton

 

Support: NIHR Biomedical Research Centre

 

In vitro investigation of plasma sprayed zinc substituted hydroxyapatite

DV Shepherd, RA Brooks, SM Best

 

Support: Orthopaedic Research U K

 

Atomic Level Structure of Extracellular Matrix

RA Brooks, R Rajan, D Reid, J Skepper, MJ Duer

 

Support: BBSRC

 

Early glycation products of collagen: a solid-state NMR spectroscopy and ultrastructural study of biological and health implications

RA Brooks, R Rajan, D Reid, J Skepper MJ Duer

 

Support: MRC

 

Academic-Industrial Initial Training Network on Innovative Biocompatible Titanium-based Structures for Orthopaedics (BioTiNet)

RA Brooks, M Golozar, L Greer, SM Best

 

Support: EU FP7

 

Actuation of Ferromagnetic Fibre Networks to improve Implant Longevity (AFFINITY)

RA Brooks, V Malheiro, R Spear, A Markaki

 

Support: EU FP7

 

ALBiON Project (click here for more details)

Zafar Ahmad, John Wardale, Roger Brooks, Davide Enea, Fran Henson, Neil Rushton

Support: TSB and EPSRC

The TSB funded project "ALBioN - Artificial Ligament with Bioactive Nanostructure (OM-DTI LigaMimetic Proj)" was aimed at investigating the application of a smart, nanocomposite material based on collagen and glycosaminoglycans the regenerative repair of torn ligaments. It would build on an existing novel biomaterials-based technology to develop a medical device product that is both compatible with existing surgical techniques and capable of improving clinical outcomes. The proposed project was intended to produce an early prototype of this device and test it in a large-animal model. The four partners in this consortium were a world-leading centre for biomaterials research; a renowned institution for preclinical and clinical orthopaedic research; a leading manufacturer of medical-grade collagen; and an SME focussed on the development of novel products for the regenerative repair of articular joint injuries.

Please click here to see our main ALBiON page for more details.

 

 

© 2012 Orthopaedic Research Unit, Department of Surgery, University of Cambridge